Educational Studies

There are literally thousands of scientific research papers published each year where various studies have been conducted on supplements, botanical extracts and foods. It is a huge task for any individual to keep up with and to consider the information that applies to them. 

Our Scientific Advisory Board continually reads and reviews all the latest journals and studies that are continually being conducted around the globe at the leading universities and medical institutions. Below are some references to studies that you can peruse for educational purposes only.

Nanoparticles of Curcumin - Safety and Benefits 

Nanoparticles of Curcumin have been found to be non-toxic and that it can prevent and reverse damage to the brain.

Professor Garg - School of Pharmacy and Medical Science, University of South Australia

Ankit Parikh, Krishna Kathawala, Jintao Li, Chi Chen, Zhengnan Shan, Xia Cao, Xin-Fu Zhou, Sanjay Garg. Curcumin-loaded self-nanomicellizing solid dispersion system: part II: in vivo safety and efficacy assessment.

Curcumin Offers Extremely Potent Antioxidant Protection 

Curcumin is an extremely potent antioxidant (more potent than Vitamin E). It positions itself within the cell membrane where it intercepts dangerous free radicals. 

Dr Gulcin - Department of Chemistry, Ataturk University, Turkey 

Ak T, Gülçin I. Antioxidant and radical scavenging properties of curcumin. Chem Biol Interact. 2008 Jul 10;174(1):27-37 

Curcumin Is a PreBiotic That Enhances Gut Biota 

The administration of Curcumin considerably changed the ratio between beneficial and harmful bacteria in the gut, favouring the growth of beneficial bacteria and limiting growth of harmful ones. 

Dr Di Meo - Institute of Biosciences and BioResources, Italy 

Di Meo F, Margarucci S, Galderisi U, Crispi S, Peluso G. Curcumin, Gut Microbiota, and Neuroprotection. Nutrients. 2019;11(10):2426. Published 2019 Oct 11. doi:10.3390/nu11102426

Curcumin protects from overactivity in Immune System 

Curcumin increases Immune system production of IL-10, a powerful anti-inflammatory that prevents over-activity of the Immune system.

Dr Mollazadeh - Department of Physiology and Pharmacology, North Khorasan University, Iran  

Mollazadeh H, Cicero AFG, Blesso CN, Pirro M, Majeed M, Sahebkar A. Immune modulation by curcumin: The role of interleukin-10. Crit Rev Food Sci Nutr. 2019;59(1):89-101

Curcumin Enhances the Immune System

Curcumin decreased inflammation and increased anti-cancer activity of Immune T Cells by 200 - 300%.

Dr Milano - Center for Experimental and Molecular Medicine, Netherlands

Milano F, Mari L, van de Luijtgaarden W, Parikh K, Calpe S, Krishnadath KK. Nano-curcumin inhibits proliferation of esophageal adenocarcinoma cells and enhances the T cell mediated immune response. Front Oncol. 2013 May 29;3:137

Curcumin Activates Cannabinoid Receptors

Curcumin nutritionally assisted the elevation of brain cannabinoids and nerve growth factor by interacting with the CB1 receptor.

Dr Hassanzadeh - Research Center for Gastroenterology and Liver Diseases, Shahid Beheshti University, Iran

Hassanzadeh P, Hassanzadeh A. The CB₁ receptor-mediated endocannabinoid signaling and NGF: the novel targets of curcumin. Neurochem Res. 2012 May;37(5):1112-20

Curcumin Anti-Inflammatory Relief in Joint Discomfort

Curcumin nutritionally assists the prevention of destruction of joint cartilage by assisting with the inhibition of inflammation. Patients with joint discomfort showed improvement in pain, physical function and quality of life after taking Curcumin. 

Dr Chin - Department of Pharmacology, Kebangsaan University, Malaysia 

Chin KY. The spice for joint inflammation: anti-inflammatory role of curcumin. Drug Des Devel Ther. 2016 Sep 20;10:3029-3042  

Vitamin D Reduces Risk of Dying from all causes

In an international study of 26,018 people, The German Cancer Research Center found low Vitamin D levels increase your risk of dying from all causes by 57%.

Dr. Schöttker - Division of Clinical Epidemiology and Aging Research, German Cancer Research Center

Schöttker B, Jorde R, Peasey A, Thorand B, Jansen EH, Groot Ld, Streppel M, Gardiner J, Ordóñez-Mena JM, Perna L, Wilsgaard T, Rathmann W, Feskens E, Kampman E, Siganos G, Njølstad I, Mathiesen EB, Kubínová R, Pająk A, Topor-Madry R, Tamosiunas A, Hughes M, Kee F, Bobak M, Trichopoulou A, Boffetta P, Brenner H; Consortium on Health and Ageing: Network of Cohorts in Europe and the United States. Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States. BMJ. 2014 Jun 17;348:g3656

Increasing Vitamin D3 Levels Improves Sleep Quality 

Low Vitamin D3 levels significantly increases risk of unhealthy sleep. Effects included short sleep duration, poor sleep quality and sleepiness. 

Dr Gao - Department of Public Health, Qingdao University 

Gao Q, Kou T, Zhuang B, Ren Y, Dong X, Wang Q. The Association between Vitamin D Deficiency and Sleep Disorders: A Systematic Review and Meta-Analysis. Nutrients. 2018 Oct 1;10(10):1395 

Vitamin D3 Is Needed by all Cells  

Nearly every cell in the body has a Vitamin D receptor. Any improvement in Vitamin D levels will significantly support more than 160 pathways linked to cancer, autoimmune disorders and cardiovascular disease. 

Dr. Holick - Boston University Medical Center 

Hossein-nezhad A, Spira A, Holick MF. Influence of vitamin D status and vitamin D3 supplementation on genome wide expression of white blood cells: a randomized double-blind clinical trial. PLoS One. 2013;8(3):e58725 

Plant Based Vitamin C is safer than Synthetic Vitamin C 

Vitamin C from food had a protective effect on arteries. Synthetic Vitamin C accelerated damage to arteries 300% 

Dr Agarwal - Cedars Sinai Heart Institute, USA 

Agarwal M, Mehta PK, Dwyer JH, et al. Differing Relations to Early Atherosclerosis between Vitamin C from Supplements vs. Food in the Los Angeles Atherosclerosis Study: A Prospective Cohort Study. Open Cardiovasc Med J. 2012;6:113-121 

Vitamin C For Joint Health  

Cartilage cells concentrate Vitamin C until it reaches 960 times the level found in surrounding tissues. 

Dr. Kraus - Department of Medicine, Duke University 

McNulty AL, Vail TP, Kraus VB. Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2. Biochim Biophys Acta. 2005 Jun 30;1712(2):212-21 

Plant Based Vitamin C more Potent than Synthetic Vitamin C 

Plant based Vitamin C has been measured to be 263x stronger per milligram when compared with synthetic Vitamin C (ascorbic acid) 

Dr. Liu - Department of Food Science, Cornell University 

Eberhardt, M, Lee C, Liu R. Antioxidant activity. Nature. 2000 Jun 22;405 903-904. 

CBDA Increases CBD Bioavailability 

Maximum blood concentration of CBD increased 400% in the presence of CBDA. 

Dr Eichler - Department of Clinical Pharmacology, University Hospital Basel, Switzerland 

Eichler M, Spinedi L, Unfer-Grauwiler S, Bodmer M, Surber C, Luedi M, Drewe J. Heat exposure of Cannabis sativa extracts affects the pharmacokinetic and metabolic profile in healthy male subjects. Planta Med. 2012 May;78(7):686-91 

Full Spectrum CBD Extract Outperforms Isolated CBD 

In stark contrast to purified CBD, the full spectrum extract had a clear correlation between anti-inflammatory, anti-pain effects and dose, the greater the dose the greater the effect. 

Dr. Gallily - The Haadassah Medical School, Hebrew University of Jerusalem 

Gallily, Ruth & Yekhtin, Zhannah & Hanus, Lumir. (2015). Overcoming the Bell-Shaped Dose-Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol. Pharmacology & Pharmacy. 06. 75-85. 10.4236/pp.2015.62010 

CBDA Has Superior Anti-Inflammatory Properties 

CBDA reduced pain with a dose 100 times smaller than that required with CBD. CBDA is more potent than CBD 

Dr Rock - Department of Psychology and Collaborative Neuroscience, University of Guelph 

Rock EM, Limebeer CL, Parker LA. Effect of cannabidiolic acid and ∆9-tetrahydrocannabinol on carrageenan-induced hyperalgesia and edema in a rodent model of inflammatory pain. Psychopharmacology (Berl). 2018 Nov;235(11):3259-3271